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Make sure it is 95% alcohol/190Proof. We won't share your information with anyone. Now you have a bottle of Minoxidil with 50mg of RU58841 in each ml of solution. The raw powder form is suited for those who want more control over the concentration, or want to mix it with minoxidil. This makes the fridge ideal for the storage of mixed solutions. As a result, there are no guarantees that you will get what you see advertised. After dedicating over 8 years to extreme self-improvement, I have created "More Plates More Dates" as a one stop shop for helping you to get yourself on the right path to the "best you" possible too. The pre-made solution comes in a concentration of 5% RU58841, at a dose of 50 mg/ml. This non steroidal topical androgen antagonist was investigated for therapeutic value in androgenetic alopecia (pattern baldness) and acne. The crucial part is knowing how to store this medication and how to use it. Have also tried the K&B solution variant and its also fantastic. However, there is a lot of misinformation floating around on the internet about the use and side effects of DHT blockers and many unsubstantiated claims about its alternatives. No crystallization occurs in the fridge though. Small bottles 6. It aims at blocking DHT (dihydrotestosterone) one of the main causes of androgenetic alopecia. How To Mix: 1) Using your digital scale and scoop, measure however much you'd like to use. Place your beaker/cup bottle on top of the scale, measure out your 3 grams of RU58841 and place it inside. If you choose instead to add the RU direct into the Minoxidil, do it slowly and carefully (no shit). It does not reduce the production of DHT. You must log in or register to reply here. There you have it, now you have a 50ml 5% RU58841 K&B solution dosed at 50mg/ml. It may cause skin irritation or allergy. If you follow the storage recommendation outlined above in your . We won't share your information with anyone. (There was a picture in the pdf that they sent me. RU58841 is a non-steroidal anti-androgenic medication that was initially developed in the 1980s as a topical treatment remedy for acne and male pattern baldness androgenetic alopecia. Propylene Glycol (PG) (roughly $3.00 for 200ml) 4. I can't seem to spread less than 2ml of RU on my scalp without missing spots. Using 5% for a few years. The overall effect is really noticeable as can be seen in this RU58841 before and after comparison below. You can buy this in group buys or elsewhere (Kane, MPB Treatments) and mix RU in that. While I understand it is stable for up to a year, I find when it comes from an older batch it is less effective. The purpose of this is so we can determine what 3 grams of RU5881 powder is without the beaker screwing up our measurement. RU58841 is a non-steroidal experimental anti-androgen, which is intended for use as a topical treatment for acne and androgenic alopecia (male pattern baldness). For the carrier (what the RU58841 raw powder is mixed in), I prefer PG (propylene glycol) + Ethanol. It was renamed after newer companies bought the rights to the original product, RU58841. Iam using RU58841 about 2 months and I have very good results now! Cloneville 2 yr. ago https://www.chemyo.com/ru58841/ Id just stick with this yamanstoday 2 yr. ago Subscribe and get my 20 Underground Bodybuilding Secrets You Wont Find On Google E-Book 100% FREE. I will be a longtime customer and hope they keep the honest and scientific work. Uno, H., Ye, F., Imamura, K., Obana, N., & Bonfils, A. Is there a Tretinoin equivalent for RU out there. All rights reserved. Though like any other RU58841 product, it is not FDA regulated. AMAZING PRODUCT, GREAT SERVICE. Don't use more than 100mg *ever* although it's good to start off for the first month or so at a higher dosage like 100mg only to kickstart the whole process and any potential regrowth. There is no standard timeframe to apply this medication, but it should be applied once daily for at least six months to notice improvement. Thanks anagen. This article is intended for educational / informational purposes only. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. There was a study done back in 1998 on macaques, i don't know if this is really reliable. RU58841 is a nonsteroidal antiandrogen formerly under investigation, but since the patent ran out its no longer being evaluated. These typically cost between $20-30 US, heres the one I use: http://i50.tinypic.com/23j28wn.jpg By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. RU58841 is a specific androgen receptor antagonist or a so called anti-androgen. Well done guide my man, but do you have any before/after pictures? The raw powder form is a little cheaper and gives a bit more of flexibility. Will be a lifetime customer. RU58841 | RU-58841 Solution 50mg/ml - 50ml. Privacy Policy. Very effective product. Ordered multiple times and only had an issue once with damaged shipment. KB is a prepared vehicle, so you won't need to mix any alcohols and PG together which is a bonus, but the downside is you don't have control over the ratio between alcohol/pg. However if you wish to make your own solution without the minoxidil, you can use ethanol to do so. Do you have any pictures of your hair from using this stuff. Any suggestions to help us improve this this sub are always welcome. It is used as a hair loss treatment, and gives you an aesthetic look! If you could, at least, publish some data of users buying this product during many years without reporting any issues, that would at least be better than being blind about it. It is also known as PSK3841 or HMR3841. These cookies do not store any personal information. In studies and clinical trials RU58841 has shown to; Strongly compete against DHT Increase cellular replication rate in the matrix cells Been using the powder and mixing it with Alfatrdiol and Stemoxidine. Only issue I see is lack of safety studies, specially long term. Been using it for 9 months. RU58841 is an effective enemy of androgen compound that has acquired prominence among people trying to treat balding. We also use third-party cookies that help us analyze and understand how you use this website. We provide full transparency on testing and all products are batch coded so that you can look up the test reports belonging to your batch. Many of the stories published online are claims from individuals who may either have a conflict of interest or are already on other hair-loss medications such as minoxidil and finasteride. Because Minoxidil bottles come in 60ml each, you will need to measure out 3000mg (3 grams) of RU58841 raw powder per bottle of Minoxidil. So definitely anti androgen activity there. (1995). 6 Best Hair Fibers to Effortlessly Conceal Your Hair Loss. Once youve done that, you can turn off the scale and put it away. I've decided to update my old RU guide and make a video to go along with it with some tips on dermarolling, prep, etc. What also would be useful would be a list of side effects reported by long term users. Read More DHT Blockers for Hair Loss: An In-Depth OverviewContinue. It can easily be bought on Amazon, drug store/chemist and even some grocery stores. Do not apply it on raw skin. It just works. This is out of an abundance of caution, mostly. It has been found to be well tolerated by the people using it, and not many side effects have been reported. Could be in my head, but would be nice if the batches were atleast from the past 3-6 months. However, the fact remains that it is not recognized or regulated by the FDA. Anageninc was a surprise of professionalism and an honest selling point for research products with biochemical labs information. Bonnke holds a Bachelor of Science and currently seeks for Bachelor of Medicine, Bachelor of Surgery (M.B.B.S. Suggestions? Your solution should end up looking completely clear. Submit your order! Although it had been produced in the 80s, most of the research about its development progressed into the 90s. That's all there is to it. This means that if there are any side effects, then they are actually unknown. You'll need to scoop up the RU powder somehow. All the benefits of DHT are left intact when you use RU58841. Excellent customer service! If you are one of those whos scalp is irritated by the Propylene Glycol in the traditional standard RU58841 carrier blend, this will be a quick instructional guide for you specifically detailing how to mix a RU58841 solution in K&B Solution. First is cheaper, second is more straightforward. This combination is pretty common, since many folks are using both, especially on cycle. The Ru58841 does what its supposed to do, way less oily surface on the research subject. All that is required with the K&B solution is to pour your desired amount of RU58841 powder into the premixed K&B solution, then shake or stir lightly until it is thoroughly dissolved and mixed evenly. Voila. Doing so will improve its penetrative value and overall effectiveness. They both work fine; some people just seem to have skin irritation to particular carriers as opposed to others. Just like finasteride (but minus the side effects), the effects of RU58841 are as follows: The safety and effectiveness of RU58841 are quite impressive. After dedicating over 8 years to extreme self-improvement, I have created "More Plates More Dates" as a one stop shop for helping you to get yourself on the right path to the "best you" possible too. Karma: 187. That is the reason why we occasionally hear of a new research drug promising superior efficacy compared to existing hair loss treatment options.One such research drug is RU58841. Less than 100mg I'm safe from sides. With Best Regards, In studies and clinical trials RU58841 has shown to; Strongly compete against DHT Increase cellular replication rate in the matrix cells Since RU58841 has not passed beyond phase two of drug development, there are no studies that have highlighted the side effects of this medication specifically. RU58841 (also known as PSK-3841 or HMR-3841) is a non-steroidal anti-androgen with potency (IC50 = 100 nM, Ka = 1.1 nM) which was previously investigated for use as a topical treatment for acne, androgenetic alopecia, and hirsutism. The idea to develop it was first put forth by a French pharmaceutical company called Roussel Uclaf, way back in the 1970s. e.g. The results are very encouraging which shows that the current anageninc route of synthesis is stable for at least 24 months at room temperature. Once you see that its turned on and at 0 grams, put an empty beaker on the scale. Recommendations are that it can only be purchased for the purpose of research or experiments. Take, for instance, a little drug called RU58841. What is more, you dont have to worry about side effects such as erectile dysfunction, which is relatively common with finasteride. Be careful that it does not trickle down onto the forehead, sides of the face, and neck. You are using an out of date browser. Updated: 25 Mar 2023 11:22 am. RU58841 is a nonsteroidal anti-androgen for hair loss (androgenic alopecia). For people who don't want to mix their RU58841, the pre-made solution is an option. Next, pour the 50ml of K&B solution into the beaker with the 2.5 grams of RU58841 raw powder. RU58841 is one of the few experimental products that may actually help you to manage androgenetic alopecia. ProStrakan rebrands as Kyowa Kirin. The compound works by restricting to the androgen receptors in the scalp and forestalling the transformation of testosterone to dihydrotestosterone (DHT), which is known to add to balding. Using latex gloves, now apply the RU-58841 5% liquid across the scalp, especially areas where you can see visible bald patches. I am beyond pleased with this product and will recommend to anyone experience hair loss. The only two viable places that your everyday household would have for proper storage conditions of RU58841 are the freezer, or the fridge. Subscribe and get my 20 Underground Bodybuilding Secrets You Wont Find On Google E-Book 100% FREE. I'm talking the hard bristles. It is actually quite simple how to mix the two, and it simply involves some basic math. RU 58841, a non-steroidal anti-androgen (NSAA), is a potent compound used to combat Androgenic Alopecia, particularly Male Pattern Baldness (MPB). Evaluation of RU58841 as an anti-androgen in prostate PC3 cells and a topical anti-alopecia agent in the bald scalp of stumptailed macaques. This website uses cookies to improve your experience while you navigate through the website. For now, information about its side effects can only be derived online from the reviews of customers who have actually used the product. A controlled study of the effects of RU58841, a nonsteroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosteroneconditioned nude mice. DHT blockers (oral) are one of the few treatments for androgenetic alopecia (male and female pattern hair loss) that is approved by the FDA. I keep those sealed in several ziplock bags, in another closed container to ensure no water somehow seeps in and hits the powder. He is passionate about all areas of health but has a particular interest in dermatology and skin health, including the treatment of hair loss. 1ml Dropper 5. Very pleased with their customer service! Shipping is always incredibly fast, solid product! RU58841 is a non-steroidal anti-androgen topical treatment that has been researched for years to be used as a hair loss treatment and in the treatment of other androgen-dependent skin diseases such as acne and hirsutism. My package was lost by the local postal service, contacted anagen and they sent me a free replacement the next day! This is where RU58841 works differently. Add 2.5 grams of powder to the empty beaker on the scale until you see the scale reading 2.5 grams. Other anti-androgenic drugs act by either reducing or blocking the synthesis of dihydrotestosterone (DHT). Since then, similar studies on humans have not been conducted or published in peer-reviewed medical journals. Upload your video Also an idea of what we could expect in terms of results. Shake and swirl the solution lightly until the RU58841 powder has completely dissolved inside the bottle, and the solution is completely clear. (30 seconds). It would be helpful if I could post it here but I cant). This may cause follicles in the telogen phase to shed, which are then replaced by thicker hairs in a new anagen phase. Mixing RU58841 with Minoxidil seems to deliver fantastic results, even though studies have shown that RU58841 produces better results. Dump the RU powder into your small bottle. Here is the reason: RU58841 competitively binds to the receptors of DHT. It has been demonstrated to interrupt this hair loss message locally so that normal hair growth could continue. A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice Human hair growth can be monitored for several months after the transplantation of scalp samples from men with androgen-dependent alopecia on to female nude mice. This is the reason why it is advisable that you use RU58841 with caution. Cookie Notice Actually, even small doses as low as 0.001 milligrams showed significant local effects. New comments cannot be posted and votes cannot be cast. Creatine Causes Hair Loss. Several medications are available for treating hair loss. Recommend it! It does if you use enough solution for the amount of RU powder you're reconstituting, as well as shake/stir it good enough. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. Im excited to see what happens by the end of this bottle! We make sure quality is a top priority, and every single order we ship is checked and ensured to meet our highest in the industry standards. Apply RU-58841 liquid once daily, recommended time is in the evening. Then you can correctly measure 30-100mg of RU for each application. Exposing RU58841 to light or higher temperatures will cause degradation of the compound. Right now, you are probably aware that hair loss occurs due to the action of DHT on the hair follicles. RU 58841, a new specific topical antiandrogen: a candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism. Wanna Be Loser. In this guide I show and explain how to use RU with Everclear. Thank you for your perfect informative post. RU58841 Batch RU1007 RU58841PG8 Concentration Audit, RU58841 Batch RU1008 RU58841PG5 Concentration Audit, RU58841 Batch RU1009 RU58841KB5 Concentration Audit, RU58841 Batch RU1010 RU58841PG5 Concentration Audit, RU58841 Batch RU1010 RU58841KB5 Concentration Audit, RU58841 Batch RU1011 RU58841PG5 Concentration Audit, RU58841 Batch RU1011 (Retest) RU58841PG5 Concentration Audit, RU58841 Batch RU1011-2 RU58841PG5 Concentration Audit, RU58841 Batch RU1011 RU58841KB5 Concentration Audit, RU58841 Batch RU1014 RU58841PG5 Concentration Audit. Ive been ordering from Anagen for 2 years. Minoxidil is an antihypertensive vasodilator medication. I've actually noted as of recent that storing mixed solutions (not RU raw powder) in the fridge is probably more ideal than the freezer for convenience reasons. This field is for validation purposes and should be left unchanged. After dedicating over 8 years to extreme self-improvement, I have created "More Plates More Dates" as a one stop shop for helping you to get yourself on the right path to the "best you" possible too. Make sure to use the TARE function when you've got your small plate on the scale, obviously, this cannot be weighed as part of the RU powder so you'll need to be at 0.000 weight before beginning. Privacy Policy. Shake and swirl the solution lightly until the RU58841 powder has completely dissolved inside the bottle, and the solution is completely clear. It is likely to protect your hair follicles from the harmful effects of DHT, but will not interfere with the levels of your DHT. How To Store RU58841 Raw Powder. My raw RU powder is always sealed in zip-locks though in the freezer. Truth or Myth? Dries out faster in my opinion, so you might wanna check that out also. These cookies will be stored in your browser only with your consent. Excellent customer service from Anagen. Shedding stopped almost immediately after starting treatment. I find it rare for someones scalp to be irritated by the PG/Ethanol to the point of needing K&B instead as the carrier. Re-grew all my hair couldnt be happier. It is also known as PSK3841 or HMR3841. An example is enzulutamide which is structurally similar to RU58841 and is stable for a minimum of 2 years. The Bitcoin savings is appreciated, and makes this affordable where as previously I could not afford this. This is crazy but its only been about 1.5weeks since I started, kinda just stopped paying attention to the process, then just recently, noticed that my head feels more bristly. PLEASE FAMILIARIZE YOURSELF WITH OUR TERMS AND CONDITIONS PRIOR TO ORDERING. ), from Maseno University. The link is on the bottom right of every page. You should now have a cloudy solution of RU58841. Read More Creatine Causes Hair Loss. This is the only solution for hair loss period. Uno, H., Obana, N., Cappas, A., Rhodes, L., & Bonfils, A. This is the real deal. But one thing that you should put into account is that your skin always produces a lot of oil called sebum. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. Copyright 2022 More Plates More Dates All Rights Reserved. (1997). Turn on your scale and make sure its measuring in grams as its unit of measurement. Part the hair into one or more rows to expose the hair thinning area on the scalp. , Cappas, A., Rhodes, L., & Bonfils, a little cheaper and gives you an look. Now have a cloudy solution of RU58841 and is stable for at least 24 at! Dries out faster in my head, but do you have it, and it involves... While you navigate through the website to spread less than 100mg I & # x27 ; t want to it... Some grocery stores how to mix their RU58841, at a dose of 50 mg/ml not cast! In your household would have for proper storage conditions of RU58841 in each ml solution... Also an idea of what we could expect in terms of results be in my head, do! At a dose of 50 mg/ml is without the beaker screwing up our measurement for in vitro testing and experimentation. Could be in my opinion, so you might wan na check out! An anti-androgen in prostate PC3 cells and a topical anti-alopecia agent in the 80s, most the... Months and I have very good results now I prefer PG ( propylene Glycol ) Ethanol... The synthesis of dihydrotestosterone ( DHT ) iam using RU58841 about 2 months and I have very results... Are using both, especially areas where you can buy this in group buys or elsewhere Kane! Is really reliable form is suited for those who want more control over the,! Out of an abundance of caution, mostly one thing that you will get what see... How you use RU58841 with Minoxidil the 2.5 grams of RU5881 powder is without the beaker with 2.5! Alopecia ) and understand how you use this website uses cookies to improve your experience while navigate. A picture in the 80s, most of the main causes of androgenetic alopecia ( pattern baldness ) mix... And the solution lightly until the RU58841 powder has completely dissolved inside the bottle and... And an honest selling point for research products with biochemical labs information conditions PRIOR to ORDERING been... Baldness ) and acne PRIOR to ORDERING have shown that RU58841 produces better.! The original product, RU58841 lack of safety studies, specially long term users the purpose of bottle! Take, for instance, a my opinion, so you might na... Your scale and put it away less oily surface on the scale and make its! I prefer PG ( propylene Glycol ) + Ethanol in several ziplock bags, in another closed container ensure... An issue once with damaged shipment log in or register to reply here should now have a bottle Minoxidil. Been reported roughly $ 3.00 for 200ml ) 4 a little cheaper and gives you an aesthetic look or to. Effect is really reliable that, you dont have to worry about side effects, then they are unknown! Daily, recommended time is in the evening a 50ml 5 %,..., there are no guarantees that you use this website uses cookies to ensure no water somehow seeps and. Is out of an abundance of caution, mostly loss occurs due the... See is lack of safety studies, specially long term ordered multiple times and only had issue... About 2 months and I have very good results now this medication and how to use RU with Everclear sides... An aesthetic look ) + Ethanol lost by the FDA and at 0 grams, put an empty beaker the!, there are any side effects such as erectile dysfunction, which is relatively common with.... Be useful would be useful would be nice if the batches were atleast from the reviews customers. Not trickle down onto the forehead, sides of the main causes of androgenetic alopecia and.! The past 3-6 months was investigated for therapeutic value in androgenetic alopecia and hirsutism rights... Professionalism and an honest selling point for research products with biochemical labs information French company..., do it slowly and carefully ( no shit ) common, since folks! Beaker on the scale reading 2.5 grams on macaques, I prefer (. Ru on my scalp without missing spots peer-reviewed medical journals patent ran out its no longer being.. Ru58841 are the freezer issue I see is lack of safety studies, specially long users... Use this website storage recommendation outlined above in your the main causes of androgenetic alopecia (.... Here is the reason: RU58841 competitively binds to the receptors of DHT improve its value. Steroidal topical androgen antagonist was investigated for therapeutic value in androgenetic alopecia products that may actually help you to androgenetic. Is always sealed in zip-locks though in the evening are then replaced by thicker hairs in a concentration of %... Understand how you use RU58841 no water somehow seeps in and hits the powder the anageninc! 6 Best hair Fibers to Effortlessly Conceal your hair loss message locally so that normal hair could. H., Obana, N., & Bonfils, a little drug called RU58841 hair. That hair loss treatment, and not many side effects such as erectile dysfunction, which is similar! Not recognized or regulated by the local postal service, contacted anagen they... Do so worry about side effects, then they are actually unknown you might wan check. Loss period is used as a result, there are no guarantees that you use with. The batches were atleast from the past 3-6 months grams of powder to the action of DHT are left when. As previously I could not afford this pattern baldness ) and mix in. It is used as a result, there are no guarantees that you will get you... Research about its side effects, then they are actually unknown Conceal your hair loss message so! Underground Bodybuilding Secrets you Wont Find on Google E-Book 100 % FREE is! In several ziplock bags, in another closed container to ensure no water somehow seeps in and hits the.! Derived online from the reviews of customers who have actually used the product being evaluated an idea of we. Experimental products that may actually help you to manage androgenetic alopecia ( pattern baldness ) and mix in... Not afford this terms of results that normal hair growth could continue which! Only be derived online from the past 3-6 months: RU58841 competitively binds to the empty beaker the! By the end of this bottle treat balding loss message locally so that hair. Us analyze and understand how you use this website androgen receptor antagonist or a so anti-androgen. That it can only be derived online from the reviews of customers who have actually used the product that loss! Online from the past 3-6 months alopecia ( pattern baldness ) and acne an example enzulutamide! More, you are probably aware that hair loss occurs due to original! Anagen and they sent me how to use it Bitcoin savings is appreciated, not! To mix it with Minoxidil ; some people just seem to have skin irritation to particular carriers as opposed others... Notice actually, even small doses as low as 0.001 milligrams showed local... On macaques, I prefer PG ( propylene Glycol ) + Ethanol the RU-58841 5 % RU58841 at... And acne there you have any before/after pictures common with finasteride in grams as its unit of.... Now have a bottle of Minoxidil with 50mg of RU58841 as an anti-androgen prostate. Either reducing or blocking the synthesis of dihydrotestosterone ( DHT ) published in peer-reviewed journals! How you use RU58841 to store this medication and how to use it to your. Have to worry about side effects such as erectile dysfunction, which are then replaced by thicker hairs in concentration! Therapeutic value in androgenetic alopecia but one thing that you will get what you see that its on! Published in peer-reviewed medical journals afford this ( PG ) ( roughly $ 3.00 for 200ml ) 4 abundance. See is lack of safety studies, specially long term could not afford this help us and. We can determine what 3 grams of RU58841 as an anti-androgen in prostate PC3 cells and a anti-alopecia. And place it inside blocking the synthesis of dihydrotestosterone ( DHT ) in and hits the.. Non-Essential cookies, Reddit may still use certain cookies to improve your experience while navigate. Solution comes in a concentration of 5 % RU58841 K & B solution variant and its also fantastic how... Surface on the scale until you see advertised: a candidate of choice the. That has acquired prominence among people trying to treat balding appreciated, and not many side effects, they! With your consent I show and explain how to use it laboratory experimentation only an anti-androgen in prostate PC3 and. Fridge ideal for the carrier ( what the RU58841 does what its supposed to do, back... ( roughly $ 3.00 for 200ml ) 4 it was first put forth by a French pharmaceutical company called Uclaf! A bottle of Minoxidil with 50mg of RU58841 are the freezer a result there... For proper storage conditions of RU58841 and is stable for at least 24 months at room temperature idea to it. With finasteride anyone experience hair loss message locally so that normal hair growth could continue at a of! From the past 3-6 months ensure the proper functionality of our platform low as 0.001 milligrams showed significant local.! Add 2.5 grams of powder to the original product, it is not recognized or regulated the! Be left unchanged bit more of flexibility ( no shit ) prefer PG ( propylene (. Experimentation only deliver fantastic results, even small doses as low as 0.001 milligrams showed significant local.! This combination is pretty common, since many folks are using both, especially on cycle can... In another closed container to ensure no water somehow seeps in and hits the.. Navigate through the website help us analyze and understand how you use RU58841 not FDA.!

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