Zhongguo Zhong.Yao Za Zhi 2009;34(21):2803-2807. View abstract. Seattle, WA: Eastland Press 1996:107-8. View abstract. View abstract. View abstract. Tseng-Crank J, Sung S, Jia Q, and et al. View abstract. Chou TC, Chang LP, Li CY, et al. Your lithium dose might need to be changed. View abstract. Bull Exp Biol Med 2002;134(1):47-49. Comparison of anti-inflammatory and anti-nociceptive activities of Curcuma wenyujin Y.H. Scutellaria barbata has been studied for its anticancer properties, but more research is needed. These include the Chinese Skullcap, Huang Qin, Scutellaria baicalensis (the scientific name), and the Hooded Willow Herb. Baikal skullcap might change how these pumps work and change how much medication stays in the body. Some medications are moved in and out of cells by pumps. Planta Med 2001;67(5):396-399. WebInhibitory effect of skullcap (Scutellaria baicalensis) extract on ovalbumin permeation in vitro and in vivo. J Chem Ecol. 2004;91(1):65-68. Neurosci Lett. Biol Pharm Bull 2003;26(1):79-83. Taking Baikal skullcap with these medications might decrease how well the medication works. Liu, S., Ma, Z., Cai, H., Li, Q., Rong, W., and Kawano, M. Inhibitory effect of baicalein on IL-6-mediated signaling cascades in human myeloma cells. Pasanen MK, Fredrikson H, Neuvonen PJ, Niemi M. Different effects of SLCO1B1 polymorphism on the pharmacokinetics of atorvastatin and rosuvastatin. Polysaccharides in S. barbata demonstrate antioxidant and free radical-scavenging activity(15). A preliminary study of S. baicalensis along with metformin appeared to improved glucose tolerance, inflammation, and gut microbiota in patients with type 2 diabetes(23). Research shows that Chinese skullcap extract is toxic to cancer cells, such as brain tumor cells, prostate cancer cells, and head and neck squamous cell carcinoma cell lines. Baicalein: an in vitro antigenotoxic compound from Scutellaria baicalensis. Memorial Sloan Kettering does not record specific website user information and does not contact users of this website. It often is used in combination with other botanicals such as PC-SPES and sho-saiko-to. Lam, T. L., Lam, M. L., Au, T. K., Ip, D. T., Ng, T. B., Fong, W. P., and Wan, D. C. A comparison of human immunodeficiency virus type-1 protease inhibition activities by the aqueous and methanol extracts of Chinese medicinal herbs. Some medications are changed and broken down by the liver. J Ethnopharmacol. Pharmacotherapy 2010;30(7):750, 258e-750, 262e. Eye contact Rinse with water. Clin Cancer Res 5-15-2005;11(10):3905-3914. Ready to start planning your care? reduce wrinkles, smooth skin) but without the side effects (though it seems now that the INCI name of Lanablue was J Biomed.Sci 2011;18:14. B., and Chun, M. Anti-inflammatory effects of Scutellaria baicalensis extract via suppression of immune modulators and MAP kinase signaling molecules. Ye, F., Xui, L., Yi, J., Zhang, W., and Zhang, D. Y. Anticancer activity of Scutellaria baicalensis and its potential mechanism. Alcohol: Alcohol interacts with Baicalin and can cause some serious Skullcap side effects like drowsiness, dizziness, and sleepiness. Naunyn-Schmiedeberg Arch Pharmacol 2006;372:432-43. In using this website you agree that neither Memorial Sloan Kettering nor any other party is or will be liable or otherwise responsible for any decision made or any action taken or any action not taken due to your use of any information presented at this website. Chinese Journal of Gerontology 2010;30(7):926-928. Regulatory effects of gibberellic acid (GA3) on shoot and root formation of Huang-qin (Scutellaria baicalensis) in vitro. Memorial Sloan Kettering was founded in 1884, and today is a world leader in patient care, research, and educational programs. 1997;11(3):125-131. 7-1-2005;382(1-2):71-75. Chen et C. Ling and Scutellaria baicalensis Georgi. Biochim Biophys Acta 1999;1472:643-50. This will help them manage your care and keep you safe. Cancer Chemother.Pharmacol 2011;67(5):1063-1072. But there is not enough information to know if Baikal skullcap is the cause of these side effects. View abstract. Baikal skullcap might change the levels of statins in your blood. FDA Alerts Consumers About Potentially Life-Threatening Health Problems Linked to Limbrel. Scientific and clinical relevance to the fact is not determined, but it is better to stay on the safer side. 1989;35(3):331-335. Chem Pharm Bull (Tokyo) 1992;40(2):531-533. WebBaicalin extracts have strong anti-inflammatory effects. Flavocoxid, a dual inhibitor of cyclooxygenase and 5-lipoxygenase, blunts pro-inflammatory phenotype activation in endotoxin-stimulated macrophages. Pediatr Dermatol 2006;23:507-10. View abstract. A., and Provalova, N. V. [The modulating effects of preparations of Baikal skullcap (Scutellaria baicalensis) on erythron reactions under conditions of neurotic exposures]. Mol Pharmacol 2001;60(3):507-513. Interactions Do not use Chinese skullcap with alcohol or the following Z., Wang, Y., and Liu, B. Baicalin induces human mucoepidermoid carcinoma Mc3 cells apoptosis in vitro and in vivo. View abstract. Some of the compounds present in this herb can work opposite and may negatively affect human beings, but many studies are not conducted related to the herb. Cancer Lett. View abstract. Ye, F., Wu, J., Dunn, T., Yi, J., Tong, X., and Zhang, D. Inhibition of cyclooxygenase-2 activity in head and neck cancer cells by genistein. View abstract. Mu, X., He, G., Cheng, Y., Li, X., Xu, B., and Du, G. Baicalein exerts neuroprotective effects in 6-hydroxydopamine-induced experimental parkinsonism in vivo and in vitro. Use of this Web site does not create an expressed or implied physician-patient relationship. Vaccine 1-8-2010;28(3):737-743. You, C. L., Su, P. Q., and Zhou, X. X. Opposite expression of securin and gamma-H2AX regulates baicalein-induced cancer cell death. Razina, T. G., Udintsev, S. N., Prishchep, T. P., and Iaremenko, K. V. [Enhancement of the selectivity of the action of the cytostatics cyclophosphane and 5-fluorouracil by using an extract of the Baikal skullcap in an experiment]. 2008;6(1):103-8. Kimura, Y., Matsushita, N., and Okuda, H. Effects of baicalein isolated from Scutellaria baicalensis on interleukin 1 beta- and tumor necrosis factor alpha-induced adhesion molecule expression in cultured human umbilical vein endothelial cells. Chinese skullcap can decrease the blood level of several drugs used to lower cholesterol levels. It is used with other herbs in traditional Chinese medicine to treat bacterial infections, hepatitis, and tumors. Am J Chin Med 2009;37(3):621-623. J Ethnopharmacol. Keep in mind that natural products are not always necessarily safe and dosages can be important. A., Sherstoboev, E. Y., Zueva, E. P., Razina, T. G., Amosova, E. N., and Krylova, S. G. Effect of baikal skullcap extract administered alone or in combination with cyclophosphamide on natural cytotoxicity system in mice with Lewis lung carcinoma. Contact Dermatitis. Zhongguo Zhong.Yao Za Zhi 2008;33(9):1064-1066. 2002;51(6):277-283. Lee, E., Enomoto, R., Suzuki, C., Ohno, M., Ohashi, T., Miyauchi, A., Tanimoto, E., Maeda, K., Hirano, H., Yokoi, T., and Sugahara, C. Wogonin, a plant flavone, potentiates etoposide-induced apoptosis in cancer cells. View abstract. View abstract. B., Blach-Olszewska, Z., and Aliev, G. Flavones from root of Scutellaria baicalensis Georgi: drugs of the future in neurodegeneration? The effect of he jie decoction on the TCRV beta 7 of chronic hepatitis B patients. Extracts were added in the amount of 2.0 g/100 g of meat batter. Int J Cancer 5-1-2007;120(9):2019-2027. 1989;35(3):331-335. Nat Prod Res 2008;22(16):1410-1412. 5-24-2006;105(3):346-351. View abstract. Baikal skullcap is also sometimes applied to the skin for psoriasis. View abstract. View abstract. Toxicology 5-2-2009;259(1-2):10-17. Shang, Y. View abstract. View abstract. There isn't enough reliable information to know what an appropriate dose of Baikal skullcap might be. Planta Med 1995;61(2):150-153. Cancer Lett. Zhou, X. Q., Liang, H., Lu, X. H., Cai, S. Q., Wang, B., and Zhao, Y. Y. View abstract. Krakauer, T., Li, B. Q., and Young, H. A. The root of Scutellaria baicalensis (SB) traditionally used for fever clearance and detoxification possesses various bioactivities including anticancer effects. Your Query - This is a community service. View abstract. Lin H, Zhou J, Lin K, et al. Int J Cancer 9-10-2003;106(4):559-565. 1997;57(1):63-67. J Ethnopharmacol. View abstract. View abstract. 2021 Jun 28;274:114052. Pulm.Pharmacol Ther 2010;23(5):411-419. Himeji, M., Ohtsuki, T., Fukazawa, H., Tanaka, M., Yazaki, S., Ui, S., Nishio, K., Yamamoto, H., Tasaka, K., and Mimura, A. 11-12-2009;126(2):320-331. In some cases, this might change the effects and side effects of a medication. Preliminary study of traditional Chinese medicine treatment of minimal brain dysfunction: analysis of 100 cases. Any questions regarding your own health should be addressed to your own physician or other healthcare provider. Ann N Y Acad Sci 2007;1095:521-526. 1-8-2007;245(1-2):269-274. Some cancer cell lines undergo cell death when exposed to extracts of this herb, but some compounds in this herb may actually have opposite effects. Lei, W., Sun, M., Luo, K. M., Shui, X. R., Sun, Y. M., and Tang, H. [Compute simulation to characterize structure and function of chalcone synthase from Scutellaria baicalensis Georgi]. View abstract. Low blood pressure: Baikal skullcap might lower blood pressure. Baikal skullcap might change how these pumps work and change how much medication stays in the body. View abstract. View abstract. Zhou, J., Qu, F., Burrows, E., Yu, Y., and Nan, R. Acupuncture can improve absorption of baicalin from extracts of Scutellaria baicalensis Georgi in rats. Phytomedicine. Successful treatment of pediatric psoriasis with Indigo naturalis composite ointment. But there is not enough information to know if Baikal skullcap is the cause of these side effects. Pasanen MK, Fredrikson H, Neuvonen PJ, Niemi M. Different effects of SLCO1B1 polymorphism on the pharmacokinetics of atorvastatin and rosuvastatin. Baikal skullcap might cause sleepiness and drowsiness. Baicalin also activated caspase-3, resulting in apoptosis of leukemia-derived T cells. View abstract. A., Han, D. Y., and Kim, G. S. Korean Scutellaria baicalensis water extract inhibits cell cycle G1/S transition by suppressing cyclin D1 expression and matrix-metalloproteinase-2 activity in human lung cancer cells. Alcohol can cause sleepiness and drowsiness. Baikal skullcap might affect the thyroid and may affect how antithyroid medications work.
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